Superior Performance

High Efficiency for a Variety of High-Sensitivity Analysis

A new turbomolecular pump with higher evacuation performance achieves a superior vacuum state in the MS unit, which also provides high sensitivity in the single GC-MS mode. With the high-efficiency collision cell (UFsweeper) installed as before, high-sensitivity detection is possible even when mass resolution is increased. The new active-time management function achieves further operating efficiencies by appropriately managing the wait times that occur during maintenance, while switching systems, or when the system is used by multiple users, to extend the operating time.

New Flow Controller Achieves Exceptional Split filter Reproducibility

A new flow controller (AFC) with a CPU uses various control methods to control carrier gas flow to a constant flow speed, flowrate, or pressure. It can also accurately trace the analytical conditions already being used. In addition, the split line filter can be replaced without any tools. Internal contamination can be confirmed visually, ensuring filters are replaced at the proper time.

Advanced GC Oven

The improved temperature control function enables more precise temperature control of the GC oven, which improves the precision of retention time reproducibility. In addition, three oven cooling rate levels can be specified to minimize damage to column liquid phases and maximize the service life.

UFsweeper™ High-Efficiency Collision Cell

Shimadzu's proprietary UFsweeper technology efficiently sweeps residual ions out of the collision cell to achieve high CID efficiency and fast ion transport. That minimizes crosstalk and enables trace analysis.

New Large-Capacity Differential Vacuum System

A more stable vacuum system was achieved by using a new turbomolecular pump that offers higher evacuation efficiency. Consequently, because it is able to maintain a high vacuum level even during MRM analysis with a collision gas (argon) introduced, it enables highly accurate trace analysis.

Detection with High Separation by High Mass Resolution

In many cases, even using MRM analysis does not provide sufficient separation for quantitative analysis of ultra-trace compounds in biological samples or food samples that contain large amounts of impurities, for example. Using the GCMS-TQ8050 NX, compounds can be detected with high sensitivity even if high mass resolution is specified. Therefore, it can clearly detect compounds that previously could not be separated from impurities.

High-Sensitivity Analysis by Single GC-MS Mode

Due to a highly sensitive ion source and highly sensitive detector with overdrive lenses, the GCMS-TQ8050 NX is able to select and detect generated ions efficiently. That achieves high sensitivity not only for MRM measurements in the GC-MS/MS mode, but also for scan and SIM measurements in the GC/MS mode. In addition, pre-rods help prevent quadrupole contamination, so that stable sensitivity and mass spectra can be obtained even when samples containing many matrices are analyzed.

Active-Time Management™ That Accurately Determines Operation Time

Time Management during Instrument Startup/Shutdown

The mass spectrometer has to be operated in a vacuum condition, the startup and stopping of the system takes time depending on the condition. Determining this can be a challenge. Since the amount of time that the system takes when starting up or stopping is displayed in real time, it is easy to accurately determine when maintenance of the ion source or analysis is possible. Moreover, tasks that until now needed to be performed by the user, such as leak checks upon system startup and auto tuning, are now performed automatically.

Time Management during Sample Injection Port Maintenance

The Easy sTop function, used to safely maintain the sample injection port without releasing the vacuum, displays the remaining time (cooling-down time) when the septum or the insert can be replaced in real time. Maintenance time can be minimized by understanding the accurate remaining time.
Furthermore, by using a ClickTek™ nut on the top of the sample injection port, the port can be opened or closed without tools, by simply using fingers to twist a lever. That enables faster and easier insert replacement than ever before.

Time Management for Continuous Analysis

By displaying the time required for continuous analysis in real time, the time when the current continuous analysis will finish can be accurately confirmed. This increases the instrument operating time (active time) by reducing standby time required during continuous analysis or while switching between different users. In addition, because this function makes it easier to schedule the timing for analysis preparations, such as sample preparation and pretreatment, based on the finish time of the previous analysis, it enables analytical processes to be performed more efficiently, which can help improve work-life balance.

Simple Column Replacement Using the Twin Line MS System


By connecting the outlet ends of two different columns to the MS at the same, different application data can be acquired without shutting OFF the MS vacuum. Since no flow restrictors are used, there are no losses from adsorption or other factors, and methods and retention times used for analysis with one column can continue to be used unchanged. The new large-capacity differential vacuum system ensures sensitivity does not decrease even when two columns are connected. Due to the separation from impurities and separation between isomers, the system can switch between different types of columns for measurements without actually replacing columns.

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